San Diego Layover, Handled
San Diego International Airport is one of the busiest single-runway airports in the world and serves as the gateway to Southern California. For business travelers, SAN offers access to the biotech hub, military contractors, and the growing tech scene in America's Finest City.
At a Glance
Best Hotels Near SAN
Hand-picked for business travelers — verified Wi-Fi, shuttle service, and workspace amenities.




Sheraton San Diego Hotel & Marina
Business travelers who want waterfront accommodations with stunning harbor views and direct downtown access.
Booking.comCheck PricesFree cancellation on most rooms




DoubleTree by Hilton San Diego Downtown
Professionals who need accommodations in the Gaslamp Quarter with easy access to the convention center and business district.
Booking.comCheck PricesFree cancellation on most rooms




Hampton Inn San Diego Downtown
Budget-conscious business travelers who need reliable downtown accommodations with complimentary breakfast and WiFi.
Booking.comCheck PricesFree cancellation on most rooms
Travel Essentials for San Diego
Gear our editors recommend for every trip to San Diego. Verified, tested, and travel-ready.

Sony WH-1000XM5
Noise-Cancelling Headphones

EPICKA Universal Adapter
All-in-One Worldwide Plug

Trtl Travel Pillow
Scientifically Proven Neck Support

Anker 737 Power Bank
24,000mAh Portable Charger

Apple AirTag 4-Pack
Track Luggage Anywhere

Kindle Paperwhite
Glare-Free 6.8" Display

Samsonite Winfield 2
Hardside Carry-On Spinner

JBL Clip 4 Speaker
Portable Waterproof Speaker
Get the San Diego Layover Guide
Free PDF: airport maps, hotel shuttles, local SIMs, and insider tips for San Diego.
San Diego Layover Tips
Proximity to Downtown
SAN is uniquely close to downtown San Diego, just 3 miles from the Gaslamp Quarter. The airport shuttle or a short taxi ride gets you to meetings quickly.
Torrey Pines Biotech Hub
The Torrey Pines area is San Diego's biotech and research hub. The area is accessible via the I-5 freeway from the airport or downtown.
Perfect Weather Advantage
San Diego enjoys 70°F (21°C) weather year-round. Business travelers can take advantage of outdoor venues and rooftop meeting spaces throughout the year.

